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To investigate whether a combination treatment of regular release levodopa (rr-l-dopa) and sustained release levodopa (sr-l-dopa) compared with monotherapy of rr-l-dopa improves sleep quality and reduces periodic limb movements (PLM) in patients with restless legs syndrome (RLS) and problems with maintaining sleep. A combination therapy of rr-l-dopa and sr-l-dopa is better than monotherapy with rr-l-dopa in reducing the frequency of PLM and problems maintaining sleep, even in patients who are severely affected. |
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